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Probability of remission with reinduction with 7+3 versus high-dose cytarabine: analysis of SWOG trial S1203
Megan Othus1, Guillermo Garcia-Manero2, Frederick R Appelbaum3,4
1Public Health Division and SWOG Statistical Center, Fred Hutchinson Cancer Center, Seattle, WA, USA. mothus@fredhutch.org.
Leukemia
|January 27, 2025
Abstract
No abstract available in PubMed .
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02:56Treatment Resistent Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...