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Bibliometric Analysis of Global Pediatric Research on Cow's Milk Protein Allergy
Xiaolan Lin1, Yifan Chen2,3, Weidong Lin1
1Department of Pediatric Gastroenterology, Fuzhou Children's Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.
Insights
Cow's milk protein allergy (CMPA) affects many children, with research growing. Future treatments for CMPA will likely involve personalized therapies targeting the gut microbiota.
Area of Science:
- Pediatric Allergy and Immunology
- Bibliometrics
- Microbiome Research
Background:
- Cow's milk protein allergy (CMPA) is a common childhood condition impacting quality of life.
- Current treatments for CMPA are palliative, costly, and do not address the root cause.
- There is a significant need for advanced understanding and novel therapeutic strategies for CMPA.
Purpose of the Study:
- To conduct a bibliometric analysis of global pediatric CMPA research.
- To identify emerging trends and future research directions in CMPA.
- To provide a comprehensive overview of the field for researchers and clinicians.
Main Methods:
- Bibliometric analysis of 2040 articles published from 2000 to 2023.
- Utilized VOS Viewer and CiteSpace software for visual analysis.
- Identified key institutions, publications, and research themes.
Main Results:
- Annual publications on pediatric CMPA show a consistent increasing trend.
- The Icahn School of Medicine at Mount Sinai is a leading institution in CMPA research.
- The Journal of Allergy and Clinical Immunology published the most influential articles.
- Current research hotspots include personalized therapy, probiotics, and gut microbiota.
Conclusions:
- Future CMPA research is expected to concentrate on personalized treatments.
- Microbiota-based interventions show promise for effective clinical application in CMPA.
- Advancements in understanding gut microbiota will drive innovative CMPA therapies.
Background:
Cow's milk protein allergy (CMPA) is a prevalent food allergy in early childhood, significantly impacting the quality of life for affected children. Current palliative measures, such as specialized formula milk, offer temporary relief but are costly and fail to address the underlying issue. Thus, there is a critical need to better understand CMPA and explore new treatment options.
Methods:
This study employed bibliometric methods to analyze global pediatric CMPA research and identify future directions for the first time. Visual analyses were conducted using VOS Viewer and CiteSpace software.
Results:
A total of 2040 articles published between 2000 and 2023 showed increasing annual publications. In this field of research, the Icahn School of Medicine at Mount Sinai has made significant contributions, with the most influential articles published in the Journal of Allergy and Clinical Immunology. Current research emphasizes personalized therapy, probiotics, and gut microbiota in CMPA.
Conclusion:
Future research will focus on microbiota-related personalized treatments, promising effective clinical interventions.

