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Automated remote temperature measurement in small animals using a telemetry/microcomputer interface.

E J Gallaher, D A Egner, J W Swen

    Computers in Biology and Medicine
    |January 1, 1985
    PubMed
    Summary
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    Researchers developed an affordable microcomputer interface for automatic data collection from radio-telemetry probes (Mini-Mitter). This system enables continuous, artifact-free temperature monitoring in small animals without constant technician supervision.

    Area of Science:

    • Animal physiology
    • Biomedical engineering
    • Data acquisition systems

    Background:

    • Accurate temperature monitoring is crucial for small animal research.
    • Handling small animals can induce stress and artifacts, affecting physiological measurements.
    • Existing methods for continuous temperature monitoring can be expensive or labor-intensive.

    Purpose of the Study:

    • To develop an inexpensive and automated system for collecting temperature data from small animals using radio-telemetry probes.
    • To overcome limitations of manual data collection and handling-induced artifacts in physiological studies.
    • To enable continuous, unattended temperature measurements in multiple animal enclosures.

    Main Methods:

    • Commercial radio-telemetry probes (Mini-Mitter) were implanted in small animals.

    Related Experiment Videos

  • A custom microcomputer interface was designed to detect and process probe signals.
  • The interface hardware converted radio signals to TTL pulse trains compatible with a Commodore PET microcomputer.
  • Custom software was developed for frequency-to-temperature conversion, sampling control, and selective cage monitoring.

    • Main Results:

    • The developed system successfully automated data collection from radio-telemetry probes.
    • The microcomputer interface accurately converted probe signals into temperature readings.
    • The system allowed for selective monitoring of up to eight individual animal cages.
    • Continuous, around-the-clock temperature measurements were achieved without technician presence.

    Conclusions:

    • The inexpensive microcomputer interface provides a reliable method for automated, artifact-free temperature monitoring in small animals.
    • This automated system significantly reduces labor costs and improves data accuracy in physiological research.
    • The technology facilitates long-term, continuous physiological data collection, enhancing the study of animal models.