Related Experiment Video
Updated: Jun 26, 2026
Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos
Published on: December 13, 2018
NELL-1 as a Target Antigen in Asbestosis Associated Membranous Nephropathy - A Case Report
Bala Sundaram1, Nabadwip Pathak2, Marie Moses Ambroise3
1Department of General Medicine, Pondicherry Institute of Medical Sciences, Kalapet, Pondicherry, India.
Abstract:
An 80-year-old male with a history of prolonged asbestos exposure presented with 24-hour urine protein of 8 gm, and serum albumin of 1.7 gm/dl. Renal biopsy disclosed features of membranous nephropathy. Immunohistochemistry showed positivity for neural epidermal-like growth factor- like 1 (NELL1) (2+/3+). Further assessment uncovered an incidental finding of asbestos-related pleural plaques and left hemithorax volume loss on computed tomography (CT) chest, leading to a diagnosis of asbestosis. This case highlights the rare association between asbestosis and NELL-1 positive membranous nephropathy.
Insights
This case report details a rare association between asbestosis and neural epidermal-like growth factor-like 1 (NELL1) positive membranous nephropathy in an elderly male patient.
Area of Science:
- Nephrology
- Pulmonology
- Pathology
Background:
- Asbestos exposure is linked to various respiratory diseases.
- Membranous nephropathy is a common cause of nephrotic syndrome in adults.
- Neural epidermal-like growth factor-like 1 (NELL1) has been implicated in some kidney diseases.
More Related Videos
07:15Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
Published on: August 23, 2024
10:21Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
Published on: September 20, 2024
