Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.0K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.0K
Stem Cell Culture01:17

Stem Cell Culture

5.1K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
5.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Machine learning-guided design of cooperative multi-size hydrogel microspheres for osteoarthritis therapy.

Biomaterials·2026
Same author

Galla Chinensis Polyphenol-Loaded Hemostatic Granules for Rapid Hemostasis, Antibacterial Action, and Wound Healing Promotion.

Journal of functional biomaterials·2026
Same author

A sulfated chitosan-driven immune-ECM reprogramming strategy to break the vicious cycle of aged wound healing.

Bioactive materials·2026
Same author

A sustained NAD<sup>+</sup> supplementation-biosynthesis nanoplatform for metabolic restoration in aged bone regeneration.

Bioactive materials·2026
Same author

Superhydrophobic Wearable Strain Sensors: From Strategic Design to Robustness Paradigm.

Nano-micro letters·2026
Same author

Glycosaminoglycan-Mimetic Sulfated Chitosan Promotes Extracellular Matrix Formation and Regulates Inflammation to Alleviate Osteoarthritis.

Bioengineering (Basel, Switzerland)·2026

Related Experiment Video

Updated: May 30, 2025

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets
09:24

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets

Published on: October 3, 2014

14.4K

Engineered biomaterials in stem cell-based regenerative medicine.

Fei Zhu1, Guangjun Nie1,2, Changsheng Liu3

  • 1CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, CAS Centre for Excellence in Nanoscience, National Centre for Nanoscience and Technology, Beijing 100190, China.

Life Medicine
|January 28, 2025
PubMed
Summary

Engineered biomaterials enhance stem cell survival and tissue regeneration for treating intractable diseases. This approach improves stem cell transplantation outcomes, offering new hope for regenerative therapies.

Keywords:
adjustable biophysical and biochemical propertiesengineered biomaterialsregenerative medicinestem cell-based regenerative therapystem cells

More Related Videos

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering
09:49

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering

Published on: February 23, 2024

1.6K
Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications
05:20

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications

Published on: May 31, 2018

14.5K

Related Experiment Videos

Last Updated: May 30, 2025

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets
09:24

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets

Published on: October 3, 2014

14.4K
Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering
09:49

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering

Published on: February 23, 2024

1.6K
Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications
05:20

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications

Published on: May 31, 2018

14.5K

Area of Science:

  • Biomaterials Science
  • Stem Cell Biology
  • Regenerative Medicine

Background:

  • Stem cell therapies show promise for degenerative and intractable diseases.
  • Challenges include poor cell survival, retention, and uncontrolled differentiation post-transplantation.
  • Various stem cell types (hematopoietic, mesenchymal, embryonic, induced pluripotent) are utilized.

Purpose of the Study:

  • To review advances in modulating stem cell behavior using engineered biomaterials.
  • To present strategies for enhancing stem cell transplantation via biomaterials.
  • To outline future directions in stem cell-based regenerative therapy.

Main Methods:

  • Review of scientific literature on engineered biomaterials and stem cell interactions.
  • Analysis of studies demonstrating biomaterial influence on cell engraftment, survival, migration, and differentiation.
  • Synthesis of current approaches combining biomaterials with stem cell transplantation.

Main Results:

  • Engineered biomaterials possess tunable properties influencing stem cell behavior.
  • Biomaterials can significantly enhance stem cell engraftment, survival, and guide tissue regeneration.
  • Combining stem cell biology with bioengineered materials improves therapeutic potential.

Conclusions:

  • Engineered biomaterials offer a promising strategy to overcome challenges in stem cell transplantation.
  • Optimizing biomaterial-stem cell interactions is crucial for successful regenerative therapies.
  • Further research into bioengineered materials will advance stem cell-based regenerative medicine.