Implementation of a Sudden Cardiac Death Risk Prediction Tool in Clinical Practice Through Electronic Health Records

Tanya Papaz1,2, Emily Seto3,4,5, Samantha J Anthony6,7,8

  • 1Genetics and Genome Biology, Research Institute, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.

CJC Open
|January 28, 2025
PubMed

Insights

Sudden cardiac death risk prediction in children with hypertrophic cardiomyopathy (HCM) is improved by implementing the PRIMaCY tool into electronic health records (EHRs). This study assesses implementation strategies for better guideline-directed care.

Area of Science:

  • Cardiology
  • Implementation Science
  • Digital Health

Background:

  • Sudden cardiac death (SCD) is a significant risk for children with hypertrophic cardiomyopathy (HCM).
  • Clinical practice guidelines recommend risk prediction tools for shared decision-making regarding implantable cardioverter-defibrillators.
  • The PRecIsion Medicine in CardiomYopathy (PRIMaCY) consortium developed a validated SCD risk prediction tool.

Purpose of the Study:

  • To implement the PRIMaCY risk prediction tool into electronic health records (EHRs) within Canadian pediatric hospitals.
  • To assess the determinants and outcomes of implementing this digital health solution.
  • To inform best practices for integrating evidence-based tools into clinical workflows.

Main Methods:

  • A prospective, multicentre, hybrid type-3 mixed-methods implementation study (INSERT-HCM).
  • Utilized the Active Implementation Framework for a staged implementation process.
  • Employed the Implementation Outcomes Taxonomy and Consolidated Framework for Implementation Research to assess outcomes and determinants.

Main Results:

  • The study focuses on the process of implementation, including technical installation and optimization for different healthcare settings.
  • Evaluation of tool adoption, penetration, and fidelity using back-end EHR data.
  • Assessment of implementation facilitators, barriers, and sustainability in clinical practice.

Conclusions:

  • Successful implementation of the PRIMaCY tool into EHRs can improve guideline-directed care for pediatric HCM patients.
  • This study will establish best practices for implementing digital health solutions within hospital EHRs.
  • Findings will guide the future dissemination of similar evidence-based digital health tools.

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