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Oral care methods to reduce salivary bacteria in infants undergoing cardiac surgery: A randomized controlled trial
Hiromi Honda1, Madoka Funahara1, Kanako Nose2
1School of Oral Health Sciences Faculty of Dentistry Kyushu Dental University, Kitakyushu, Japan.
Insights
Systemic antibiotics significantly reduced oral bacteria after pediatric cardiac surgery. Postoperative antiseptic mouthwash with povidone-iodine (PV-I) further decreased bacterial counts in infants.
Area of Science:
- Pediatric Surgery
- Microbiology
- Infectious Disease Prevention
Background:
- Postoperative complications like pneumonia are risks after pediatric cardiac surgery.
- Limited research exists on perioperative oral bacterial changes in these patients.
- Understanding oral flora dynamics is crucial for infection control.
Purpose of the Study:
- To investigate changes in oral bacterial counts in infants undergoing cardiac surgery.
- To evaluate the impact of antiseptic mouthwash on postoperative oral bacteria.
- To assess the effectiveness of different oral care interventions.
Main Methods:
- 102 infants with congenital heart disease underwent surgery.
- Salivary bacterial counts were measured pre- and post-oral care.
- Postoperative groups received water, benzethonium chloride (BZ), or povidone-iodine (PV-I) mouthwash.
- Bacterial counts were assessed before and after oral care in each group.
Main Results:
- Preoperative oral care did not alter bacterial counts.
- Postoperative bacterial counts were lower, likely due to antibiotics.
- No significant difference in bacterial counts between water and BZ groups post-care.
- PV-I mouthwash significantly reduced bacterial counts post-care.
Conclusions:
- Systemic antibiotics effectively reduce postoperative oral bacteria in infants.
- Povidone-iodine (PV-I) mouthwash provides additional bacterial reduction.
- Antiseptic oral care can be a valuable adjunct in preventing complications.
Background/Purpose:
Complications, such as postoperative pneumonia, can occur after pediatric cardiac surgery; however, studies on related changes in perioperative oral bacterial counts are scarce. Herein, we investigated the changes in oral bacterial counts before and after surgery in infants who underwent cardiac surgery, as well as after oral care using an antiseptic mouthwash.
Materials And Methods:
A total of 102 infants who underwent congenital heart disease surgery were enrolled in this study. Preoperative oral care was provided using water and a sponge brush. Bacterial cultures were used to determine salivary bacterial counts before and after oral care. Postoperatively, the infants were randomized into a water group (WA group), benzethonium chloride mouthwash group (BZ group), or povidone-iodine mouthwash group (PV-I group), and their salivary bacterial counts, before and after oral care, were measured.
Results:
The preoperative salivary bacterial colony counts did not change after oral care; however, the postoperative bacterial counts were significantly lower, possibly because of the use of systemic antibiotics. Bacterial counts before and after oral care were not significantly different between the WA and BZ groups; however, bacterial counts were significantly decreased in the PV-I group after oral care.
Conclusion:
Overall, the results of this study show that systemic administration of antibiotics reduces postoperative salivary bacterial counts in infants undergoing cardiac surgery, and oral care with PV-I can further reduce bacterial counts.
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