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Updated: Jun 13, 2025
Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
Published on: December 20, 2024
Incidentally discovered inflammatory pseudotumour of the spleen: understanding clinical manifestations and diagnosis
Dylan Quinn1, Bryant Morocho2, David Bertsch3
1Geisinger Commonwealth School of Medicine, Scranton, Pennsylvania, USA.
Abstract:
A splenic inflammatory pseudotumour (IPT) is a rare condition in which inflammatory cells and non-cancerous specialised cells known as myofibroblasts abnormally replicate in the spleen. Patients with IPT may experience symptoms like abdominal pain, fever and weight loss, making it difficult to distinguish from processes like cancer. As a result, diagnosing IPT often requires imaging studies and microscopic examination.Here, we present a case of a woman in her 60s with a history significant for acute myeloid leukaemia now in remission who presented with abdominal pain and constitutional symptoms. Imaging revealed a new 3 cm mass in her spleen. A biopsy of the mass followed by removal confirmed the identity of the mass as an IPT. Following the operation, the patient recovered without complications. This case underscores the importance of considering IPT when diagnosing splenic masses as well as considering surgical removal to achieve a definitive diagnosis.
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