Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aging01:26

Aging

36
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
36
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

2.0K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.0K
Mitochondria01:37

Mitochondria

10.0K
Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
10.0K
Positive Regulator Molecules01:45

Positive Regulator Molecules

105.7K
To consistently produce healthy cells, the cell cycle—the process that generates daughter cells—must be precisely regulated.
105.7K
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

2.5K
The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
2.5K
Electron Transport Chain: Complex I and II01:46

Electron Transport Chain: Complex I and II

10.7K
The mitochondrial electron transport chain (ETC) is the main energy generation system in the eukaryotic cells. However, mitochondria also produce cytotoxic reactive oxygen species (ROS) due to the large electron flow during oxidative phosphorylation. While Complex I is one of the primary sources of superoxide radicals, ROS production by Complex II is uncommon and may only be observed in cancer cells with mutated complexes.
ROS generation is regulated and maintained at moderate levels necessary...
10.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multicomponent Micelles with Boosted Stability of Iminoboronates.

Biomacromolecules·2026
Same author

Polyphenol-based nanoparticles enhancing doxycycline efficacy for acne therapy.

Journal of materials chemistry. B·2026
Same author

Bioadhesive polydopamine-vitamin A derivative hydrogels reprogram the wound microenvironment for scarless wound healing and hair follicle regeneration.

Materials horizons·2026
Same author

A Degradable Macromolecular Antioxidant for Efficient Arthritis Treatment.

Biomacromolecules·2025
Same author

Disulfide-Functionalized Covalent Organic Frameworks as Nanocarriers Realizing Programmed Cellular Internalization and Drug Release.

ACS applied materials & interfaces·2025
Same author

Direct polymerization of tyrosine conjugates into melanin-like polymers for efficient protection of photosensitive pesticides.

Materials horizons·2025
Same journal

<i>Materials Horizons</i> Emerging Investigator Series: Dr Yao Liu, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, China.

Materials horizons·2026
Same journal

Universal cryo-thermal sculpting of transition metal dichalcogenides: simultaneous phase and size engineering for energy electrocatalysis.

Materials horizons·2026
Same journal

Synergistic protein-reinforced DNA hydrogels with tunable biomechanics for mechanoresponsive drug release.

Materials horizons·2026
Same journal

Harnessing stereochemically active Sn-chemistry to engineer exciton localization in core-shell halide perovskite nanocrystals.

Materials horizons·2026
Same journal

Geometry-driven multimodal tactile sensors with high-fidelity perception enabled by strain-invariant oxidized liquid metal electrodes.

Materials horizons·2026
Same journal

Recent progress and perspectives of catalytic ammonia synthesis.

Materials horizons·2026
See all related articles

Related Experiment Video

Updated: May 30, 2025

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence
13:59

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence

Published on: August 12, 2018

8.1K

One-component anti-aging agents.

Rong Zhang1, Bo Liang2, Wanjie Bai1

  • 1College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China. ywli@scu.edu.cn.

Materials Horizons
|January 29, 2025
PubMed
Summary
This summary is machine-generated.

A new one-component poly(coumarin) agent effectively combats polymer photo-oxidation by absorbing UV light and neutralizing free radicals. This versatile material enhances polymer stability and shows promise for food packaging applications.

More Related Videos

Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application
03:47

Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application

Published on: September 27, 2024

766
Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ
10:05

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

Published on: May 8, 2020

1.9K

Related Experiment Videos

Last Updated: May 30, 2025

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence
13:59

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence

Published on: August 12, 2018

8.1K
Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application
03:47

Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application

Published on: September 27, 2024

766
Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ
10:05

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

Published on: May 8, 2020

1.9K

Area of Science:

  • Polymer Science
  • Materials Chemistry
  • Photochemistry

Background:

  • Polymer photo-oxidation aging degrades plastics, reducing performance and lifespan.
  • Current multi-component anti-aging agents present synthesis, processing, and environmental challenges.
  • There is a critical need for robust, multi-functional, one-component anti-aging solutions.

Purpose of the Study:

  • To develop and evaluate a novel class of one-component poly(coumarin) anti-aging agents.
  • To assess the UV absorption and antioxidant capabilities of poly(coumarin) agents.
  • To explore their potential for enhancing polymer photostability and food packaging.

Main Methods:

  • Enzymatic polymerization of coumarin to synthesize poly(coumarin) agents.
  • Spectroscopic analysis to determine UV absorption spectrum.
  • Computational calculations (O-H bond dissociation energy, reaction energy barrier) to evaluate radical scavenging ability.
  • Comparative performance assessment against commercial UV-shielding and antioxidant agents.

Main Results:

  • Poly(coumarin) agents demonstrated broader UV absorption and higher antioxidative capacity than commercial standards (UV326, AO1010).
  • Calculations confirmed effective UV attenuation and free radical scavenging properties.
  • The material significantly improved polymer anti-aging properties.

Conclusions:

  • One-component poly(coumarin) nanoparticles offer a promising solution for polymer photo-oxidation.
  • These agents can enhance polymer photostability and are suitable for food preservation packaging.
  • Poly(coumarin) represents a versatile, multi-functional alternative to conventional multi-component anti-aging systems.