Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Engineering cells for solid tumor therapy.

Trends in pharmacological sciences·2026
Same author

Animal models of idiopathic membranous nephropathy: Recent advances and future perspectives.

Animal models and experimental medicine·2026
Same author

Multidimensional Differences and Driving Mechanisms of Bacterial Communities in Urban and Rural Rivers Across China.

Microorganisms·2026
Same author

Contribution of resting pulse rate to fall risk prediction in patients with glaucoma: a nationwide retrospective study based on an XGBoost model.

BMC ophthalmology·2026
Same author

Development and Internal Validation of a Nomogram for Predicting Reflux Esophagitis in Candidates for Metabolic Bariatric Surgery.

Obesity surgery·2026
Same author

Optimization of IS621 recombinase/bridge RNA-directed recombination for precise insertion of large DNA fragments in human cells.

Nature communications·2026

Related Experiment Video

Updated: May 30, 2025

Author Spotlight: Simple Establishment of a Vascularized Osteogenic Bone Marrow Niche Using Pre-Cast Poly(Ethylene Glycol) (PEG) Hydrogels in an Imaging Microplate
10:32

Author Spotlight: Simple Establishment of a Vascularized Osteogenic Bone Marrow Niche Using Pre-Cast Poly(Ethylene Glycol) (PEG) Hydrogels in an Imaging Microplate

Published on: May 19, 2023

2.5K

Versatile hydrogels prepared by microfluidics technology for bone tissue engineering applications.

Luyue Zhang1, Liqian Su2, Lina Wu3

  • 1State Key Laboratory of Oral Disease & National Center for Stomatology & National Clinical Center for Oral Diseases & Department of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China. jxsun@scu.edu.cn.

Journal of Materials Chemistry. B
|January 29, 2025
PubMed
Summary

Microfluidics combined with tissue engineering offers advanced hydrogels for bone regeneration. These microfluidic-prepared hydrogels show promise for improved bone defect treatments and regenerative medicine.

More Related Videos

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs
10:19

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs

Published on: August 8, 2022

1.8K
An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components
08:17

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

7.1K

Related Experiment Videos

Last Updated: May 30, 2025

Author Spotlight: Simple Establishment of a Vascularized Osteogenic Bone Marrow Niche Using Pre-Cast Poly(Ethylene Glycol) (PEG) Hydrogels in an Imaging Microplate
10:32

Author Spotlight: Simple Establishment of a Vascularized Osteogenic Bone Marrow Niche Using Pre-Cast Poly(Ethylene Glycol) (PEG) Hydrogels in an Imaging Microplate

Published on: May 19, 2023

2.5K
Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs
10:19

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs

Published on: August 8, 2022

1.8K
An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components
08:17

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

7.1K

Area of Science:

  • Regenerative Medicine
  • Biomaterials Science
  • Microfluidics

Background:

  • Bone defects from trauma, disease, or surgery present significant clinical challenges.
  • Existing bone regeneration methods have limitations in efficacy and application.
  • Tissue engineering and microfluidics integration offers a novel approach to bone regeneration.

Purpose of the Study:

  • To classify microfluidic devices for bone tissue engineering (BTE).
  • To review microfluidic methods for hydrogel preparation in BTE.
  • To highlight the advantages of microfluidic-derived hydrogels over conventional ones for bone regeneration.

Main Methods:

  • Classification of microfluidic devices based on flow, channel type, materials, and techniques.
  • Overview of microfluidic techniques for hydrogel preparation.
  • Discussion of organ-on-a-chip models and diagnostic/therapeutic applications of microfluidics in BTE.

Main Results:

  • Microfluidic preparation yields hydrogels with controlled cargo release, suitability for in situ injection, simplified cell encapsulation, and high-throughput precision.
  • Organ-on-a-chip models provide authentic environments for studying cell and tissue dynamics.
  • Microfluidic devices enable noninvasive diagnosis and therapy for bone conditions.

Conclusions:

  • Microfluidically prepared hydrogels offer significant advantages for bone tissue engineering compared to traditional methods.
  • Preclinical and clinical applications of these hydrogels are advancing regenerative medicine for bone defects.
  • Future research should address current limitations and challenges to fully realize the potential of microfluidics in bone regeneration.