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Updated: May 30, 2025

A Protocol for Transcranial Photobiomodulation Therapy in Mice
Published on: November 18, 2018
Optimal Timing of Photobiomodulation Therapy for Retinal Diseases: Leveraging Circadian Mitochondrial Rhythms
1Rubens Siqueira Research Center, São Jose do Rio Preto, Brazil.
Abstract:
Age-related retinal degeneration is associated with mitochondrial dysfunction. Emerging evidence suggests that photobiomodulation therapy (PBMT) using near-infrared light may improve mitochondrial function and visual performance, but its efficacy is critically time-dependent. This article explores how daily biological rhythms and mitochondrial function interact, focusing on the potential of timed PMBT for age-related eye diseases. Further research is needed to determine optimal treatment times and individual responses to maximize this therapy's benefits.
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