Emergence, Transmission, and Containment of Candida auris in the Perioperative Setting

AORN Journal
|January 29, 2025
PubMed

Insights

Candida auris is a multidrug-resistant fungus spreading globally, causing severe infections in healthcare settings. Strict infection control measures are crucial to prevent its spread, especially in vulnerable patients.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Candida auris is an emerging multidrug-resistant fungal pathogen.
  • It poses a significant threat in healthcare settings due to its persistence and ability to cause severe infections.
  • Global spread and numerous outbreaks have been reported since its identification in 2009.

Purpose of the Study:

  • To highlight the threat of Candida auris in healthcare settings.
  • To emphasize the importance of infection prevention and control strategies.
  • To underscore the need for continued research and education.

Main Methods:

  • Literature review on Candida auris epidemiology, virulence, and clinical impact.
  • Analysis of its characteristics, including multidrug resistance and biofilm formation.
  • Review of recommended infection prevention and control measures.

Main Results:

  • Candida auris exhibits unique virulence factors like biofilm formation and immune evasion.
  • Immunocompromised patients and those undergoing invasive procedures are most vulnerable.
  • Effective strategies include hand hygiene, environmental cleaning, PPE, early detection, and isolation.

Conclusions:

  • Candida auris is a resilient and difficult-to-eradicate fungus.
  • Vigilance and adherence to infection control protocols are essential for patient safety.
  • Ongoing research and education are vital for combating this emerging threat.

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