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Area of Science:

  • Dermatology
  • Immunology
  • Vaccinology

Background:

  • Annular atrophic lichen planus (AALP) is a rare, chronic subtype of lichen planus.
  • AALP typically shows resistance to conventional topical steroid treatments.
  • The precise pathogenesis of AALP, potentially involving dermal inflammatory responses, is not fully understood.

Purpose of the Study:

  • To report a rare case of AALP developing post-vaccination.
  • To discuss the potential link between vaccination and AALP development.
  • To review factors influencing AALP and its treatment response.

Main Methods:

  • Case study presentation.
  • Clinical observation of lesion development and progression.
  • Review of existing literature on vaccine-induced lichen planus and AALP.

Main Results:

  • A 54-year-old female developed AALP lesions on her trunk and extremities after vaccination.
  • The patient's condition was confirmed approximately one year after symptom onset.
  • The case illustrates a rare instance of vaccine-associated dermatological reaction.

Conclusions:

  • Vaccination can be a rare trigger for lichen planus, including the AALP subtype.
  • AALP presents a diagnostic and therapeutic challenge due to its resistance to standard treatments.
  • Further investigation into vaccine-induced AALP is warranted to understand its pathogenesis and optimize management.