Related Experiment Video
Updated: May 30, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Engaging Patients in Discussions About Medication Deprescribing
Jacquelyn Pendergast1, Jolie B Wormwood2,3, Kelly Stolzmann2
1Center for Health Optimization and Implementation Research, VA Boston Healthcare System and VA Bedford Healthcare System, Boston and Bedford, MA, USA. Jacquelyn.Pendergast@va.gov.
Patient-directed educational brochures increase deprescribing discussions with primary care providers (PCPs). Engaging with brochures and prior PCP contact significantly boosts these conversations, promoting shared decision-making.
Area of Science:
- Gerontology
- Health Literacy
- Patient Engagement
Background:
- Deprescribing, the intentional reduction or discontinuation of medications, aims to minimize inappropriate use and medication-related harm.
- Patient involvement in deprescribing conversations can enhance the likelihood of medication changes and support shared decision-making.
Purpose of the Study:
- To evaluate the effect of patient-focused educational materials on patient engagement and initiation of deprescribing discussions with primary care providers (PCPs).
Main Methods:
- A study involved mailing medication-specific brochures to patients two weeks before their PCP appointments.
- Surveys were sent post-appointment to assess patient-reported deprescribing discussions and brochure engagement.
- Multivariable logistic regression analyzed factors associated with deprescribing discussions.
Main Results:
- Patient characteristics like higher education and adequate health literacy were linked to increased deprescribing discussions.
- Active engagement with brochure activities, pre-appointment PCP contact, and discussing the brochure with others also significantly increased discussion likelihood.
- Conversely, Black patients were less likely to report deprescribing discussions compared to White patients.
Conclusions:
- Patient engagement with educational materials and individual characteristics significantly influence deprescribing discussions.
- Patient-centered brochures can empower patients, integrating their perspectives into deprescribing decisions.
- Future research should focus on implementation strategies to improve deprescribing reach, especially for patients with lower health literacy.
Related Concept Videos
Drug Therapy
Antianxiety Medications
Antidepressant Drugs: Overview
Techniques of Therapeutic Communication II: Focusing, Paraphrasing, and Summarizing
This therapeutic technique can also be used when a patient brings up pertinent information during a health-related conversation. The...
Drug Abuse and Addiction: Pharmacological Phenomena
Psychosis: Goals of Pharmacotherapy
Antidepressant Drugs: MAOIs and Other Agents

