Risk factor assessment for post-thrombolytic coronary angiogram normalcy in young myocardial infarction patients

Area of Science:

• Cardiology
• Internal Medicine

Background:

• Acute myocardial infarction (AMI) is a leading cause of global mortality, accounting for over 15% annually.
• AMI involves the abrupt cessation of blood flow to cardiac muscle, posing a critical health risk.

Purpose of the Study:

• To evaluate the effectiveness of thrombolysis in young patients with acute coronary syndrome (ACS).
• To compare the recovery outcomes of young AMI patients with hypertension versus diabetes.

Main Methods:

• A cohort of 433 young patients with acute coronary syndrome (myocardial infarction) were treated with fibrin-specific agents.
• Patients underwent diagnostic coronary angiography between September 2021 and October 2022.
• Odds ratios were calculated to compare recovery rates.

Main Results:

• The odds ratio for recovery in young hypertensive patients was 1.973.
• This value is significantly higher compared to individuals with diabetes (0.306).
• Approximately 25.9% of young patients with hypertension demonstrated improved recovery through thrombolysis.

Conclusions:

• Hypertension is a significant factor associated with better recovery outcomes in young myocardial infarction patients treated with thrombolysis.
• Identifying and managing risk factors like hypertension are crucial for preventing AMI.
• Early intervention, education, and lifestyle modifications are key to improving cardiovascular health and preventing myocardial infarction.