Risk factor assessment for post-thrombolytic coronary angiogram normalcy in young myocardial infarction patients

Venkatramani Mahadevan1, Abirami Karuppiah2, Shravan Venkatraman3

  • 1Department of Cardiology, Stanley Medical College, Chennai, India.

Insights

Acute myocardial infarction (AMI) is a life-threatening condition. Young patients with hypertension showed a higher recovery chance with thrombolysis compared to those with diabetes.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Acute myocardial infarction (AMI) is a leading cause of global mortality, accounting for over 15% annually.
  • AMI involves the abrupt cessation of blood flow to cardiac muscle, posing a critical health risk.

Purpose of the Study:

  • To evaluate the effectiveness of thrombolysis in young patients with acute coronary syndrome (ACS).
  • To compare the recovery outcomes of young AMI patients with hypertension versus diabetes.

Main Methods:

  • A cohort of 433 young patients with acute coronary syndrome (myocardial infarction) were treated with fibrin-specific agents.
  • Patients underwent diagnostic coronary angiography between September 2021 and October 2022.
  • Odds ratios were calculated to compare recovery rates.

Main Results:

  • The odds ratio for recovery in young hypertensive patients was 1.973.
  • This value is significantly higher compared to individuals with diabetes (0.306).
  • Approximately 25.9% of young patients with hypertension demonstrated improved recovery through thrombolysis.

Conclusions:

  • Hypertension is a significant factor associated with better recovery outcomes in young myocardial infarction patients treated with thrombolysis.
  • Identifying and managing risk factors like hypertension are crucial for preventing AMI.
  • Early intervention, education, and lifestyle modifications are key to improving cardiovascular health and preventing myocardial infarction.
Abstract