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Updated: May 30, 2025

Myocardial Infarction and Functional Outcome Assessment in Pigs
Published on: April 25, 2014
Risk factor assessment for post-thrombolytic coronary angiogram normalcy in young myocardial infarction patients
Venkatramani Mahadevan1, Abirami Karuppiah2, Shravan Venkatraman3
1Department of Cardiology, Stanley Medical College, Chennai, India.
Insights
Acute myocardial infarction (AMI) is a life-threatening condition. Young patients with hypertension showed a higher recovery chance with thrombolysis compared to those with diabetes.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Acute myocardial infarction (AMI) is a leading cause of global mortality, accounting for over 15% annually.
- AMI involves the abrupt cessation of blood flow to cardiac muscle, posing a critical health risk.
Purpose of the Study:
- To evaluate the effectiveness of thrombolysis in young patients with acute coronary syndrome (ACS).
- To compare the recovery outcomes of young AMI patients with hypertension versus diabetes.
Main Methods:
- A cohort of 433 young patients with acute coronary syndrome (myocardial infarction) were treated with fibrin-specific agents.
- Patients underwent diagnostic coronary angiography between September 2021 and October 2022.
- Odds ratios were calculated to compare recovery rates.
Main Results:
- The odds ratio for recovery in young hypertensive patients was 1.973.
- This value is significantly higher compared to individuals with diabetes (0.306).
- Approximately 25.9% of young patients with hypertension demonstrated improved recovery through thrombolysis.
Conclusions:
- Hypertension is a significant factor associated with better recovery outcomes in young myocardial infarction patients treated with thrombolysis.
- Identifying and managing risk factors like hypertension are crucial for preventing AMI.
- Early intervention, education, and lifestyle modifications are key to improving cardiovascular health and preventing myocardial infarction.
Objectives:
Acute myocardial infarction is a critical medical condition that poses a significant risk to life. It is distinguished by the abrupt cessation of blood flow to a specific segment of the cardiac muscle. Acute myocardial infarction accounts for more than 15 % of global mortality annually.
Methods And Results:
A total of 433 young patients admitted with acute coronary syndrome - myocardial infarction underwent thrombolysis with fibrin specific agents followed by underwent diagnostic coronary angiogram between 01.09.2021 and 31.10.2022. The odds ratio showed a value of 1.973, which is much higher than the individuals with diabetes (0.306). Young individuals (25.9 %) with hypertension have a greater chance of recovery by thrombolysis.
Conclusions:
The factors that contribute for the myocardial infarction should be recognized and addressed. Recognizing and addressing these risk factors through education, lifestyle modifications, and early intervention are crucial for preventing myocardial infarction and promoting good health.

