Related Experiment Video
Updated: May 30, 2025

05:12
Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
Published on: May 12, 2023
3.6K
Primary Leiomyosarcoma of the Thyroid
Wala Ben Kridis1, Dhouha Sakka2, Ines Saguem3
1Department of medical oncology, Habib Bourguiba Hospital, University of Sfax, Sfax, 3029, Tunisia. walabenkridis@yahoo.fr.
Head and Neck Pathology
|January 30, 2025
Summary
Primary thyroid leiomyosarcoma (LMS) is rare. This case study details a 43-year-old man with right thyroid lobe LMS who achieved complete remission through surgery, radiation, and chemotherapy.
Area of Science:
- Endocrinology
- Oncology
- Pathology
Background:
- Leiomyosarcoma (LMS) is a rare malignant mesenchymal neoplasm.
- Primary LMS of the thyroid gland is exceptionally uncommon, representing only 0.014% of all LMS cases.
Purpose of the Study:
- To report a rare case of primary leiomyosarcoma of the thyroid gland.
- To describe the successful multimodal treatment and complete remission of a thyroid LMS patient.
Main Methods:
- Case report of a 43-year-old male patient.
- Surgical resection of the thyroid tumor.
- Post-operative radiation therapy and chemotherapy.
Main Results:
- Complete remission of the leiomyosarcoma was achieved.
- The patient demonstrated successful outcomes following the combined treatment approach.
Conclusions:
- Multimodal therapy including surgery, radiation, and chemotherapy can be effective for thyroid leiomyosarcoma.
- This case highlights the importance of considering rare malignancies and aggressive treatment strategies.
Related Concept Videos
The Thyroid Gland
3.5K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
3.5K
Synthesis and Regulation of Thyroid Hormones
4.1K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.1K
Functions of Thyroid Hormones
2.5K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.5K

