Related Experiment Video
Updated: Jul 1, 2026
Technique to Collect Fungiform Taste Papillae from Human Tongue
Published on: September 18, 2010
Solitary Fibrous Tumor of the Tongue: a Case Report
Anne Evelyn Oliveira Moura1, Evelyne Pedroza de Andrade2, Thiago Coelho Gomes da Silva3
1Oral Diagnosis Department, Semiology and Oral Pathology Areas, Piracicaba Dental School, University of Campinas (UNICAMP), Av. Limeira, 901, Bairro Areão, Piracicaba, São Paulo, Brazil. aeomoura@gmail.com.
Introduction:
Solitary fibrous tumor (SFT) is a fibroblastic neoplasm of uncertain biological origin that is rare in the tongue.
Case Report:
A 42-year-old woman presented with a painless, submucosal nodule in the tongue. Based on the clinical hypothesis of benign mesenchymal neoplasia, the lesion was excised, and the specimen was submitted for histopathological analysis. Microscopically, a proliferation of spindle cells with a patternless arrangement was observed, separated by dilated and angulated vascular spaces. Immunohistochemical analysis revealed positivity for CD34, CD99, Bcl-2, Ki-67 (< 5%), and negativity for S-100. Additionally, the tumor cells showed a positive nuclear reaction for STAT6. The diagnosis was a solitary fibrous tumor.
Conclusions:
This report presents a case of SFT in the tongue, emphasizing its clinicopathological, microscopic, and immunohistochemical features.
More Related Videos
Related Concept Videos
01:01Tongue
Anatomical Position in the Oral Cavity
The tongue is located within the oral cavity, also known as the mouth. It is attached to the floor of the mouth by a fold of mucous membrane called the...
01:26Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.