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Updated: May 30, 2025

JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics
Published on: October 19, 2021
Parallel median consensus clustering in complex networks
Md Taufique Hussain1, Mahantesh Halappanavar2, Samrat Chatterjee2
1Department of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA. mth@iu.edu.
Abstract:
We develop an algorithm that finds the consensus among many different clustering solutions of a graph. We formulate the problem as a median set partitioning problem and propose a greedy optimization technique. Unlike other approaches that find median set partitions, our algorithm takes graph structure into account and finds a comparable quality solution much faster than the other approaches. For graphs with known communities, our consensus partition captures the actual community structure more accurately than alternative approaches. To make it applicable to large graphs, we remove sequential dependencies from our algorithm and design a parallel algorithm. Our parallel algorithm achieves 35x speedup when utilizing 64 processing cores for large real-world graphs representing mass cytometry data from single-cell experiments.
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