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Psychological Inflexibility, Cognitive Fusion, and Thought-Action Fusion as a Transdiagnostic Construct: Direct
Sang Won Lee1,2, Seung Jae Lee1,3, Mina Choi4
1Department of Psychiatry, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Psychiatry Investigation
|January 31, 2025
Summary
Psychological inflexibility, cognitive fusion, and thought-action fusion (TAF) appear to be transdiagnostic factors for major depressive disorder (MDD) and obsessive-compulsive disorder (OCD). These factors moderately explain symptoms in both conditions, suggesting shared therapeutic targets.
Area of Science:
- Psychology
- Clinical Psychology
- Psychiatry
Background:
- Acceptance and Commitment Therapy (ACT) processes are recognized as transdiagnostic factors in major depressive disorder (MDD) and obsessive-compulsive disorder (OCD) individually.
- Limited research directly compares these transdiagnostic factors across MDD and OCD.
Purpose of the Study:
- To identify potential transdiagnostic factors associated with ACT across MDD, OCD, and healthy control (HC) groups.
- To directly compare these factors between MDD and OCD patients.
Main Methods:
- Recruited 34 MDD patients, 43 OCD patients, and 46 HCs.
- Administered the Acceptance and Action Questionnaire-II, Cognitive Fusion Questionnaire, and thought-action fusion (TAF) scale.
- Utilized symptom severity scales for depression and OCD.
Main Results:
- Clinical groups (MDD and OCD) exhibited higher psychological inflexibility, cognitive fusion, and TAF likelihood compared to HCs.
- No significant differences in these factors were found between MDD and OCD groups.
- These factors explained 26% of depressive symptoms in MDD and 27% of OCD symptoms in the OCD group.
Conclusions:
- Psychological inflexibility, cognitive fusion, and TAF likelihood are confirmed as potential transdiagnostic factors for MDD and OCD.
- These factors moderately contribute to the primary symptoms of both disorders.
- Future research should explore how ACT addresses disorder-specific variations beyond these transdiagnostic factors.
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