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Related Experiment Video

Updated: May 30, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
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Psoriasis in People With Skin of Color: An Evidence-Based Update.

Maria-Angeliki Gkini1, Mio Nakamura2, Andrew F Alexis3

  • 1Department of Dermatology, Royal London Hospital,Barts Health NHS Trust, London, UK.

International Journal of Dermatology
|January 31, 2025
PubMed
Summary

Psoriasis impacts individuals with skin of color (SOC) differently, often presenting more severely and affecting quality of life (QoL) more profoundly. People with SOC receive less biologic treatment, highlighting a need for more research and equitable care.

Keywords:
disparitiesepidemiologyethnicitygeneticspsoriasisquality of liferaceskin of colortreatment

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Area of Science:

  • Dermatology
  • Immunology
  • Public Health

Background:

  • Psoriasis exhibits global variations in epidemiology, genetics, clinical presentation, and management.
  • Historically, limited data exists on psoriasis characteristics in individuals with skin of color (SOC).

Purpose of the Study:

  • To provide an evidence-based update on psoriasis in individuals with skin of color (SOC).
  • To highlight differences in presentation, impact, and treatment in SOC populations.

Main Methods:

  • Literature search from January 2018 to August 2023 in PubMed, MEDLINE, and Cochrane Library.
  • Inclusion of studies with I-III level of evidence based on Oxford Centre for Evidence-Based Medicine recommendations.

Main Results:

  • Psoriasis prevalence is lower in SOC but tends to be more severe.
  • Individuals with SOC experience a worse quality of life (QoL) impact compared to White populations.
  • People with SOC are less likely to receive biologic treatments.

Conclusions:

  • Multiple factors contribute to differences in psoriasis clinical features and therapeutic nuances in SOC populations.
  • Further research is crucial to understand psoriasis variations in diverse populations and improve global patient care outcomes.
  • Inconsistent definitions of ethnicity, race, and SOC limit generalizability of current findings.