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Updated: May 30, 2025

Light-driven Enzymatic Decarboxylation
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Published on: May 22, 2016

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Visible Light-Mediated Decarboxylative Giese Addition Utilizing Thioxanthone or Thioxanthone-TfOH Complex as the

Charikleia S Batsika1, Naya A Stini1, Christoforos G Kokotos1

  • 1Laboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian Un, iversity of Athens, Panepistimiopolis, Athens, 15771, Greece.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|January 31, 2025
PubMed
Summary

This study introduces a green, metal-free photochemical method for organic synthesis. It utilizes carboxylic acids and thioxanthone photocatalyst for efficient 1,4-radical conjugate additions under LED light.

Keywords:
Giese additionPhotochemistryRadical additionThioxanthoneTriflic acid

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