Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hand hygiene

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...

Drugs for Treatment of Diarrhea-Predominant IBS

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...

Immunodeficiency Diseases

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...

Inflammatory Bowel Disease I: Ulcerative Colitis

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...

Peroxisomes

Peroxisomes

Peroxisomes are specialized organelles present in fungi, plant, and animal cells. It can vary in number, size, morphology, and activity depending on the type of tissue and the nutritional state of the cell. For example, cells with active lipid metabolism, such as adipocytes, neurons, and hepatocytes, have more peroxisomes than other cells in the body. Besides their primary role in breaking down complex organic molecules, peroxisomes can also synthesize specific macromolecules and participate in...

Peptic Ulcer Disease I: Introduction

Peptic Ulcer Disease I: Introduction

Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...

Search research articles

Home
Research Domains
Chemical Sciences
Inorganic Chemistry
Inorganic Chemistry Not Elsewhere Classified
Rare Acute Generalized Exanthematous Pustulosis Caused By Iodixanol: A Case Report.

Home
Research Domains
Chemical Sciences
Inorganic Chemistry
Inorganic Chemistry Not Elsewhere Classified
Rare Acute Generalized Exanthematous Pustulosis Caused By Iodixanol: A Case Report.

Related Experiment Video

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Rare acute generalized exanthematous pustulosis caused by iodixanol: A case report.

Xiuxiu Ma^1,2, Chaozhu He², Xiaohong Zeng^1,2

¹School of Nursing, Nanchang University, First Clinical Medical College, Jiangxi Medical College, Nanchang University, Jiangxi, China.

|January 31, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

This case report details a rare instance of acute generalized exanthematous pustulosis (AGEP) triggered by iodixanol contrast media. Prompt allergen avoidance and supportive care led to the patient's full recovery without recurrence.

More Related Videos

Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Related Experiment Videos

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Area of Science:

Dermatology
Radiology
Allergology

Background:

Acute generalized exanthematous pustulosis (AGEP) is a rare, severe delayed allergic reaction, predominantly drug-induced.
Iodixanol, a contrast agent, is an infrequently reported cause of AGEP, with limited global and no reported cases in China.

Purpose of the Study:

To report a rare case of AGEP induced by iodixanol in a Chinese patient.
To highlight the clinical presentation, diagnostic findings, and management of iodixanol-induced AGEP.

Main Methods:

A case study of a 35-year-old female patient who developed AGEP after iodixanol administration for CT scanning.
Clinical observation, laboratory blood tests (WBC, neutrophils, CRP, IL-10), and skin biopsy for histopathological examination.
Treatment involved immediate allergen avoidance, corticosteroids, antihistamines, cyclosporine, and human immunoglobulin.

Main Results:

The patient presented with widespread erythema and sterile pustules, accompanied by elevated inflammatory markers and immune indicators.
Histopathology confirmed immune cell infiltration in the superficial dermis.
One-year follow-up showed complete resolution of symptoms and increased patient awareness of allergen prevention.

Conclusions:

The case exemplifies a severe, rare presentation of AGEP, characterized by pruritus, edema, erythema, pustules, and desquamation.
Discontinuation of iodixanol and symptomatic treatment resulted in successful recovery without recurrence.
Further research may lead to more standardized and scientific use of iodinated contrast media.