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Updated: May 30, 2025

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CFO: Calibration-Free Odds Bayesian Designs for Dose Finding in Clinical Trials

Jialu Fang1, Ninghao Zhang1, Wenliang Wang1

  • 1School of Computing and Data Science, The University of Hong Kong, Hong Kong, China.

JCO Clinical Cancer Informatics
|January 31, 2025
PubMed
Summary

We developed user-friendly R and Shiny software for implementing advanced calibration-free odds (CFO) type designs in clinical trials. These tools enhance dose-finding accuracy and efficiency by integrating randomization and various CFO design variants.

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