Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Gastrulation

Gastrulation

Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Arthroscopic reconstruction of anterior cruciate ligament with preservation of the remnant bundle].

Zhongguo gu shang = China journal of orthopaedics and traumatology·2013

Same author

[Anterior cruciate ligament reconstruction with tendon graft enveloped by preserved remnants].

Zhongguo gu shang = China journal of orthopaedics and traumatology·2013

Same author

Genetic and molecular biological characterization of two homologous cheR genes from Leptospira interrogans.

Acta biochimica et biophysica Sinica·2013

Same author

Upregulation of glycoprotein nonmetastatic B by colony-stimulating factor-1 and epithelial cell adhesion molecule in hepatocellular carcinoma cells.

Oncology research·2013

Same author

Effect of implantation of biodegradable magnesium alloy on BMP-2 expression in bone of ovariectomized osteoporosis rats.

Materials science & engineering. C, Materials for biological applications·2013

Same author

[Texture variation of CC 5052 aluminum alloy slab from surface to center layer by XRD].

Guang pu xue yu guang pu fen xi = Guang pu·2013

Search research articles

Related Experiment Video

Updated: May 3, 2026

A Semi-high-throughput Imaging Method and Data Visualization Toolkit to Analyze C. elegans Embryonic Development

A Semi-high-throughput Imaging Method and Data Visualization Toolkit to Analyze C. elegans Embryonic Development

Published on: October 29, 2019

Decoding the blueprints of embryo development with single-cell and spatial omics.

Chang Liu¹, Xuerong Li², Qinan Hu³

¹BGI Research, Hangzhou 310030, China; BGI Research, Shenzhen 518083, China; Shanxi Medical University-BGI Collaborative Center for Future Medicine, Shanxi Medical University, Taiyuan 030001, China; Shenzhen Proof-of-Concept Center of Digital Cytopathology, BGI Research, Shenzhen 518083, China.

Seminars in Cell & Developmental Biology

|January 31, 2025

Summary

Single-cell and spatial omics technologies provide unprecedented insights into embryonic development. These advanced methods reveal complex gene expression and cellular changes, enhancing our understanding of developmental processes.

Keywords:

Developmental defects Embryonic development Organogenesis Single-cell sequencing Spatial omics

More Related Videos

Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells

Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells

Published on: January 7, 2020

Author Spotlight: A Pipeline to Analyze Lineage-Specific Mutant Embryos at Single-Cell Resolution

Author Spotlight: A Pipeline to Analyze Lineage-Specific Mutant Embryos at Single-Cell Resolution

Published on: June 14, 2024

Related Experiment Videos

Last Updated: May 3, 2026

A Semi-high-throughput Imaging Method and Data Visualization Toolkit to Analyze C. elegans Embryonic Development

A Semi-high-throughput Imaging Method and Data Visualization Toolkit to Analyze C. elegans Embryonic Development

Published on: October 29, 2019

Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells

Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells

Published on: January 7, 2020

Author Spotlight: A Pipeline to Analyze Lineage-Specific Mutant Embryos at Single-Cell Resolution

Author Spotlight: A Pipeline to Analyze Lineage-Specific Mutant Embryos at Single-Cell Resolution

Published on: June 14, 2024

Area of Science:

Developmental Biology
Genomics
Molecular Biology

Background:

Embryonic development involves precise regulation of cell differentiation, morphogenesis, and gene expression.
Recent technological advancements enable high-throughput profiling at the single-cell level.

Purpose of the Study:

To review the latest single-cell and spatial multi-omic technologies.
To catalog their applications in studying embryonic development.
To explore current and future potential of these technologies.

Main Methods:

Review of single-cell sequencing techniques.
Analysis of spatial transcriptomics methodologies.
Examination of multi-omic data analysis algorithms.

Main Results:

Single-cell and spatial omics offer multifaceted perspectives on embryonic development.
These technologies provide detailed insights into cellular and molecular mechanisms.
Spatial transcriptomics offers unique advantages for understanding tissue organization.

Conclusions:

Single-cell and spatial multi-omic technologies are revolutionizing the study of embryonic development.
Continued evolution of these technologies promises deeper understanding of developmental processes.
Widespread adoption is anticipated to significantly advance the field.