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Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
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Related Experiment Video

Updated: May 29, 2025

Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways

Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways

Published on: January 13, 2016

The Microbiome and Pulmonary Immune Function.

Jennifer M Baker¹, Robert P Dickson²

¹Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.

Clinics in Chest Medicine

|January 31, 2025

Summary

This summary is machine-generated.

The lung microbiome, or respiratory microbiota, plays a key role in lung immunity and disease. Future research will focus on developing therapies that target the lung microbiome to modulate immune responses.

Keywords:

Immunocompromised host Lung microbiome Microbial ecology Pulmonary immunity

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Last Updated: May 29, 2025

Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways

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Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

Area of Science:

Pulmonary immunology
Microbiome research
Translational medicine

Background:

The lung microbiome field has significantly advanced in the past decade.
Emerging evidence links respiratory microbiota to lung immunity and pathogenesis.
This area is crucial for translational and clinical research.

Purpose of the Study:

To review recent insights into the lung microbiome's impact on pulmonary immune function.
To identify key areas for future investigation.
To inform the development of novel immunomodulatory therapies.

Main Methods:

Literature review of recent studies on the lung microbiome and immune function.
Synthesis of current knowledge on the interplay between respiratory microbiota and the host immune system.
Identification of research gaps and future directions.

Main Results:

The lung microbiome is increasingly recognized for its significant role in regulating pulmonary immune responses.
Specific microbial compositions are associated with distinct immune profiles and disease states.
Understanding these interactions is vital for advancing lung health.

Conclusions:

The lung microbiome is a critical factor in maintaining pulmonary immune homeostasis.
Further research is essential to harness the therapeutic potential of the respiratory microbiome.
Targeting the lung microbiome offers promising avenues for developing new treatments for lung diseases.