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Frequency of CMV testing during pregnancy-a retrospective study
A Hadjiiona1, I Michaelides2, P Kummer3
1University Department of Obstetrics and Gynecology, Clinic St. Hedwig of The Order of St. John, University of Regensburg, Steinmetzstrasse 1-3, 93049, Regensburg, Germany. antigoni.hadj@gmail.com.
Archives of Gynecology and Obstetrics
|January 31, 2025
Summary
Cytomegalovirus (CMV) testing is crucial for pregnant women due to congenital infection risks. In Upper Palatinate, Bavaria, only 40.3% of pregnant women were tested, highlighting a gap in routine prenatal care for this common viral infection.
Area of Science:
- Virology
- Maternal-Fetal Medicine
- Public Health
Background:
- Cytomegalovirus (CMV) is a widespread herpesvirus.
- Congenital CMV infections pose significant risks to fetal health.
- Vertical transmission can lead to severe newborn complications.
Purpose of the Study:
- To assess the frequency of CMV testing in pregnant women in Upper Palatinate, Bavaria.
- To evaluate the prevalence of CMV seropositivity and primary infections in this cohort.
- To highlight the status of CMV diagnostics as an individual healthcare service in Germany.
Main Methods:
- Retrospective analysis of 1000 pregnant patients (aged 17-45) at University Clinic St. Hedwig, Regensburg.
- Review of medical records to determine CMV testing status and results.
- Data collection on patient demographics and serological outcomes.
Main Results:
- 59.7% of pregnant women did not undergo CMV testing.
- Among tested patients (40.3%), 35.5% were seropositive, 63.8% seronegative, and 0.74% had a primary infection.
- A significant proportion of pregnant women in the region were not screened for CMV.
Conclusions:
- CMV diagnostics are not standard in German maternity guidelines, often incurring full patient costs.
- Early diagnosis and hygiene measures are vital for preventing maternal seroconversion and fetal infection.
- While antiviral treatments exist, the absence of a CMV vaccine necessitates proactive screening and prevention strategies.
