Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Low plasma fibronectin after drowning.

L K Hansen, I Brandslund, D Johannessen

    Intensive Care Medicine
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Complement C3d is not associated with axial spondyloarthritis and magnetic resonance imaging changes at the sacroiliac joint.

    Scandinavian journal of rheumatology·2021
    Same author

    Highly sensitive quantification of optic neuritis intrathecal biomarker CXCL13.

    Multiple sclerosis and related disorders·2020
    Same author

    Chitin-calcium alginate composite fibers for wound care dressings spun from ionic liquid solution.

    Journal of materials chemistry. B·2020
    Same author

    Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study.

    Journal of neuroinflammation·2019
    Same author

    New drug candidates for depression - a nationwide population-based study.

    Acta psychiatrica Scandinavica·2018
    Same author

    Patient-controlled hospital admission for patients with severe mental disorders: a nationwide prospective multicentre study.

    Acta psychiatrica Scandinavica·2018
    Same journal

    Advances in ventilator-associated pneumonia: from pathophysiology to precision management.

    Intensive care medicine·2026
    Same journal

    Rethinking phenotyping in acute respiratory failure: systemic inflammation can be infectious or noninfectious.

    Intensive care medicine·2026
    Same journal

    Letters to the editor or correspondence written opaquely by AI/LLMs: a rising plague in science, but on whose shoulders does the onus of proof lie?

    Intensive care medicine·2026
    Same journal

    Vitamin C in acute critical illness: don't confuse pharmacotherapy and nutrition!

    Intensive care medicine·2026
    Same journal

    Lung- and diaphragm-protective mechanical ventilation in acute respiratory distress syndrome.

    Intensive care medicine·2026
    Same journal

    60 years of ARDS and the evolution of extracorporeal lung support - from ECMO to ECCO<sub>2</sub>R.

    Intensive care medicine·2026
    See all related articles

    Low fibronectin levels in a drowning victim indicated severe reticulo-endothelial failure for 8 days. This suggests fibronectin may serve as a prognostic marker for drowning and asphyxia cases.

    Area of Science:

    • Biochemistry
    • Pathophysiology
    • Clinical Medicine

    Background:

    • Fibronectin is a crucial glycoprotein involved in cell adhesion and immune response.
    • Reticulo-endothelial system (RES) dysfunction is a critical factor in severe trauma and shock.
    • Assessing fibronectin levels can offer insights into RES function and patient prognosis.

    Observation:

    • A 53-year-old male presented with zero plasma fibronectin concentrations for 8 days post-submersion (5 minutes).
    • The patient experienced multiple organ failure and disseminated intravascular coagulation.
    • The patient ultimately succumbed to his condition 15 days after the incident.

    Findings:

    • Sustained absence of plasma fibronectin correlated with prolonged and severe reticulo-endothelial failure.

    Related Experiment Videos

  • The observed fibronectin depletion suggests a significant impairment of the reticulo-endothelial system's phagocytic capacity.

    • Implications:

    • Plasma fibronectin levels may serve as a valuable prognostic indicator in cases of drowning.
    • Monitoring fibronectin could aid in predicting outcomes for patients suffering from asphyxia due to various causes.
    • This case highlights the potential role of fibronectin as a biomarker for systemic inflammatory response and organ failure.