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Related Concept Videos

Blind Procedures02:07

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Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
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Related Experiment Video

Updated: May 29, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
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Sleeping Behavior and Keratoconus: A Scoping Review.

Alejandro Tello, Paula Alejandra Navarro, Angelica Pedraza-Concha

    Ceska a Slovenska Oftalmologie : Casopis Ceske Oftalmologicke Spolecnosti a Slovenske Oftalmologicke Spolecnosti
    |February 1, 2025
    PubMed
    Summary
    This summary is machine-generated.

    Sleeping positions may influence keratoconus (KC) development. Prone or lateral sleeping may increase corneal stress, but more research is needed to confirm this link for keratoconus (KC).

    Keywords:
    Corneaasymmetric keratoconuskeratoconussleepsleeping behavior

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    Area of Science:

    • Ophthalmology
    • Corneal Diseases
    • Biomechanical Engineering

    Background:

    • Keratoconus (KC) is a progressive eye condition affecting corneal shape.
    • Nocturnal eye compression from sleeping postures is a potential, under-investigated factor in KC.
    • Asymmetry in KC may be influenced by external biomechanical forces during sleep.

    Purpose of the Study:

    • To review existing literature on the association between sleeping positions and keratoconus (KC).
    • To determine if nocturnal eye compression from sleep posture contributes to KC development or asymmetry.
    • To synthesize evidence on the biomechanical impact of sleep positions on corneal health.

    Main Methods:

    • A systematic scoping review of multiple databases (CENTRAL, MEDLINE, EMBASE, LILACS, ClinicalTrials.gov) and gray literature.
    • Inclusion criteria focused on studies examining sleeping positions (prone, lateral, supine) and KC.
    • Analysis of 10 studies with 2,322 participants, categorized by analytical and non-analytical designs.

    Main Results:

    • 50% of studies (non-analytical) indicated a correlation between KC parameters and nocturnal eye compression.
    • 60% of analytical studies (3 out of 5) reported a statistically significant association between sleeping positions and KC risk.
    • Evidence suggests a potential link between prone/lateral sleeping and KC development/asymmetry.

    Conclusions:

    • Prone and lateral sleeping positions may contribute to keratoconus (KC) development or asymmetry.
    • These positions might increase corneal biomechanical stress during sleep.
    • Further research is essential to validate findings and elucidate causal mechanisms.