Hyperglycemia as a Rare Cause of Quadriplegia: A Case Report

Osmotic demyelination syndrome (ODS) [mostly central pontine myelinosis (CPM)] is mainly reported with rapid correction of hyponatremia and very rarely with hyperglycemia. We report a very rare case of a young male presenting with altered mentation and quadriplegia due to hyperglycemia-induced pontine and extrapontine myelinosis. To our knowledge, it is the first case where both structures were involved in a single patient. The presentation of ODS depends upon the areas (pontine or extrapontine) of the brain involved, ranging from mild tremor to seizure, encephalopathy, and quadriplegia.