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Related Experiment Video

Updated: May 29, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
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Endoscopic Surgery for Deeply Located Intracranial Cysts: Risk Factors for Re-Operation and Symptom Improvement.

Jun Kyu Hwang1, Ju-Seong Kim2, Eun Kyung Park3

  • 1Department of Neurosurgery, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea.

Yonsei Medical Journal
|February 2, 2025
PubMed
Summary

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Endoscopic fenestration effectively treats deeply located intracranial cysts (DLICs), with most patients improving after one surgery. Female sex and infancy increase re-operation risk for these cysts.

Area of Science:

  • Neurosurgery
  • Pediatric Neurosurgery
  • Minimally Invasive Surgery

Background:

  • Deeply located intracranial cysts (DLICs) present unique surgical challenges.
  • Endoscopic fenestration offers a minimally invasive approach to managing these lesions.

Purpose of the Study:

  • To evaluate the efficacy of endoscopic fenestration for DLICs.
  • To identify risk factors for re-operation and poor symptom improvement.

Main Methods:

  • A retrospective analysis of 51 patients with DLICs treated via endoscopic fenestration.
  • Patients were followed for a median of 32 months, with cyst volumes assessed by MRI.

Main Results:

  • Endoscopic fenestration significantly reduced DLIC volume by 45.4% over 32 months.
Keywords:
Endoscopycentral nervous systemcystsrisk factors

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  • 76.5% of patients experienced symptom improvement after a single procedure.
  • Infants (<12 months) and females had significantly higher re-operation rates and lower symptom improvement.

    • Conclusions:

    • Endoscopic fenestration is a feasible and effective treatment for DLICs.
    • Female sex and age under 12 months are identified as significant risk factors for re-operation and reduced symptom improvement.