Related Experiment Video
Updated: May 29, 2025

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
Published on: May 17, 2019
Returning to work after breast cancer: a longitudinal analysis of employment and financial hardship
Enoch Park1, Lindsay Peterson2, Shawn McKeon2
1School of Medicine, Saint Louis University, 1402 S Grand Blvd, St Louis, MO, 63104, USA. enoch.park@health.slu.edu.
Purpose:
This study explored changes in employment and financial hardship following breast cancer diagnosis.
Methods:
We used data from a single-institution, longitudinal study of women with newly diagnosed breast cancer who received curative intent chemotherapy. The primary outcomes of interest in this analysis were breaks in active employment, defined as being out of work for the four weeks prior, and patient-reported acute financial burden during chemotherapy and up to 24 months following chemotherapy completion. Mixed-effects logistic regression models were used to identify factors associated with breaks in employment and financial burden.
Results:
The cohort consisted of 104 women who were employed at time of breast cancer diagnosis. The mean age was 49.6 years and 86% were non-Hispanic White, 11% African American or Black, and 4% another race or ethnicity. In multivariable models, African-American women were 168% more likely to report a break from active employment than their non-Hispanic white counterparts (adjusted odds ration [aOR] 2.68; p = 0.026). A break from active employment was not statistically associated with greater self-reported acute financial burden, but patients from the lowest socioeconomic status tertile were 173% more likely to report financial burden than those in the highest tertile (aOR 2.73; p = 0.022).
Conclusion:
African-American breast cancer survivors were more likely to report breaks from active employment than their White peers, even after adjusting for type of work and socioeconomic status.
Implication For Cancer Survivors:
African-American and Black breast cancer survivors may face greater challenges returning to work.
Related Concept Videos
Cancer Survival Analysis
Longitudinal Research
Longitudinal Studies
Introduction To Survival Analysis
The primary goal of survival analysis is to estimate survival time—the time...
Comparing the Survival Analysis of Two or More Groups
Actuarial Approach
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...

