Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy.

Area of Science:

• Oncology
• Medical Physics
• Radiotherapy

Background:

• Cancer treatment necessitates advanced therapies targeting tumors while preserving patient quality of life.
• Hadron Therapy (HT), utilizing charged particles like protons and carbon ions, provides superior precision over conventional methods.
• Despite 70 years of development and widespread patient use, HT requires further innovation for global accessibility.

Purpose of the Study:

• To review the current state and future directions of Hadron Therapy in oncology.
• To highlight the need for cost-effective and compact accelerator technologies for broader HT implementation.
• To discuss emerging innovations that could enhance HT accessibility and efficacy.

Main Methods:

• Review of historical development and current applications of Hadron Therapy.
• Analysis of technological advancements in particle accelerators for cancer treatment.
• Exploration of novel therapeutic modalities and delivery techniques, including BNCT and FLASH therapy.

Main Results:

• Hadron Therapy has treated over 400,000 patients worldwide with protons and carbon ions.
• Significant advancements are being made in accelerator technology, image-guidance, and treatment protocols.
• Emerging techniques like Boron Neutron Capture Therapy (BNCT) and FLASH therapy show promise for improved outcomes.

Conclusions:

• Hadron Therapy is a maturing yet continuously evolving field in cancer treatment.
• Technological innovation, particularly in affordability and compactness, is crucial for expanding global access.
• Ongoing research and development in areas like BNCT, image-guided delivery, and FLASH therapy will further benefit cancer patients worldwide.