Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA as a Genetic Template02:05

DNA as a Genetic Template

21.6K
Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
21.6K
Conservation of Protein Domains Over Different Proteins02:26

Conservation of Protein Domains Over Different Proteins

10.8K
Protein domains are small structurally independent units that are part of a single amino acid chain.  Although these domains are often structurally independent, they may rely on synergistic effects to perform their functions as part of a larger protein. Protein domains may be conserved within the same organism, as well as across different organisms.
A limited set of protein domains often duplicate and recombine during evolution. These domains can be organized in different combinations to...
10.8K
Protein Folding01:25

Protein Folding

7.7K
Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
Protein Structure Is Critical to Its Biological Function
Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...
7.7K
The Replisome03:01

The Replisome

32.9K
DNA replication is carried out by a large complex of proteins that act in a coordinated matter to achieve high-fidelity DNA replication. Together this complex is known as the DNA replication machinery or the replisome.
The synthesis of the leading and lagging strands is a highly coordinated process. To explain this, the “Trombone model” was proposed by Bruce Alberts in 1980. The DNA loop formation starts when a primer is synthesized on the parent lagging strand. The loop grows with...
32.9K
From DNA to Protein03:06

From DNA to Protein

17.9K
The flow of genetic information in cells from DNA to mRNA to protein is described by the central dogma, which states that genes specify the sequence of mRNAs, which in turn specify the sequence of amino acids making up all proteins. The decoding of one molecule to another is performed by specific proteins and RNAs. Because the information stored in DNA is so central to cellular function, it makes intuitive sense that the cell would make mRNA copies of this information for protein synthesis...
17.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

COX-2 inhibition improves immune system homeostasis and decreases liver damage in septic rats.

The Journal of surgical research·2009
Same author

Mass spectral characterization of organophosphate-labeled, tyrosine-containing peptides: characteristic mass fragments and a new binding motif for organophosphates.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences·2009
Same author

3D-SURFER: software for high-throughput protein surface comparison and analysis.

Bioinformatics (Oxford, England)·2009
Same author

Total arch replacement with stented elephant trunk technique: a proposed treatment for complicated Stanford type B aortic dissection.

Journal of cardiac surgery·2009
Same author

Top-emitting white organic light-emitting devices with a one-dimensional metallic-dielectric photonic crystal anode.

Optics letters·2009
Same author

[Detection of tick and tick-borne pathogen in some ports of Inner Mongolia].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2009
Same journal

Bifacial Perovskite Solar Cells by Lamination Approach With a PEDOT:PSS/d-Sorbitol Blended Adhesion Layer.

Small methods·2026
Same journal

Dual-Sided Interface Optimization Enables High-Brightness All-Solution-Processed ZnMgO-Based Green Perovskite QLEDs.

Small methods·2026
Same journal

Intelligent Sensing Gloves Enabled by Liquid Metal Atomized Spraying for Shared Human-Machine Interaction.

Small methods·2026
Same journal

Confinement-Amplified Tritiated Water Clean-Up in Functionalized Graphene Oxide Nanochannels.

Small methods·2026
Same journal

Optimizing the Development Process in Direct Photolithography for Efficient PeLEDs.

Small methods·2026
Same journal

Fluorinated Diluents Enable Crowded Solvation Environments to Form Anion-Rich SEIs for High-Performance Potassium-Ion Batteries.

Small methods·2026
See all related articles

Related Experiment Video

Updated: May 29, 2025

Simple, Affordable, and Modular Patterning of Cells using DNA
08:59

Simple, Affordable, and Modular Patterning of Cells using DNA

Published on: February 24, 2021

4.0K

Recent Advances in DNA-Templated Protein Patterning.

Qinglin Xia1,2, Mo Zhou1,2,3, Kai Jiao4

  • 1Division of Physical Biology, CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.

Small Methods
|February 3, 2025
PubMed
Summary
This summary is machine-generated.

DNA nanotechnology precisely organizes materials using DNA templates. This review covers DNA-templated protein patterns for biomimetic complexes, with applications in diagnostics and therapeutics.

Keywords:
DNA nanotechnologybiomedical engineeringbiomimetic materialsprotein patterns

More Related Videos

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

11.0K
Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
10:23

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Published on: May 8, 2015

11.6K

Related Experiment Videos

Last Updated: May 29, 2025

Simple, Affordable, and Modular Patterning of Cells using DNA
08:59

Simple, Affordable, and Modular Patterning of Cells using DNA

Published on: February 24, 2021

4.0K
DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

11.0K
Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
10:23

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Published on: May 8, 2015

11.6K

Area of Science:

  • Biotechnology
  • Nanotechnology
  • Molecular Biology

Background:

  • DNA nanotechnology enables precise nanoscale organization of functional materials.
  • DNA-templated protein patterns are emerging as tools for programming biomimetic protein complexes.

Purpose of the Study:

  • To summarize recent advancements in DNA-templated protein patterning.
  • To discuss applications in biological analysis and biomedicine.
  • To highlight the potential of DNA-protein patterns in precision diagnostics and therapeutics.

Main Methods:

  • Review of cutting-edge methods for arranging proteins using DNA templates.
  • Analysis of protein patterns across various dimensions.
  • Discussion of fabrication techniques and their challenges.

Main Results:

  • DNA-templated protein patterning allows for controlled arrangement of proteins.
  • These patterns have diverse applications in biological analysis and biomedicine.
  • Programmable DNA-protein patterns show promise for advanced diagnostics and therapeutics.

Conclusions:

  • DNA-templated protein patterning is a rapidly advancing field with significant potential.
  • Further research is needed to overcome fabrication challenges and fully realize applications.
  • This technology offers exciting opportunities in precision medicine and diagnostics.