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From Diabetes to Neuropathy: A Diagnostic Journey to Leigh Syndrome

Arya Behzadi1, Pooya Poormehr1, Hedyeh Saneifard1

  • 1Department of pediatric endocrinology and metabolism, Mofid children's hospital, Shahid Beheshti university of medical sciences, Tehran, Iran.

Iranian Journal of Child Neurology
|February 3, 2025
PubMed

Insights

Leigh syndrome, a rare mitochondrial disorder, can present with unusual diabetes symptoms and neurological deficits in children. Early recognition of rare causes like this is crucial for effective pediatric diabetes management.

Area of Science:

  • Pediatric Endocrinology
  • Mitochondrial Genetics
  • Neurology

Background:

  • Diabetes mellitus is a prevalent chronic disorder characterized by hyperglycemia.
  • Leigh syndrome is a rare genetic mitochondrial disorder often presenting with neurological deficits.
  • Unusual presentations of diabetes in pediatric populations necessitate consideration of rare etiologies.

Keywords:
DiabetesLeigh syndromeNeurological disorders Mitochondrial disorders Genetic testing

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