Endocrine Mucin-Producing Carcinoma: A Case Report With Distinctive Immunohistochemical Features and Correlation With...

This case report describes a rare case of an endocrine mucin-producing carcinoma (EMPC) in an 84-year-old male patient presenting with a cutaneous lesion in the left infraorbital region. EMPC is a rare cutaneous neoplasm characterized by the presence of basaloid cells that produce mucin, alongside features of neuroendocrine differentiation. It often poses diagnostic challenges due to its histological overlap with other skin tumors, such as basal cell carcinoma and mucinous carcinoma. The patient underwent outpatient surgery for the excision of the lesion and reconstruction with a Mustardé-like local flap. Histological examination revealed an ulcerated neoplasm composed of mucin-secreting basaloid cells with focal neuroendocrine differentiation. This case is discussed in the context of the existing literature on EMPC.