Related Experiment Video

Updated: Aug 12, 2026

A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice
09:58

A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice

Published on: April 13, 2010

The prevalence and natural history of wheezing in early childhood

D P Strachan

    The Journal of the Royal College of General Practitioners
    |April 1, 1985
    PubMed

    Insights

    Early onset of childhood wheeze generally indicates a better prognosis for respiratory illness. Parental recall of early wheezing symptoms is often incomplete, potentially skewing prevalence data.

    Area of Science:

    • Pediatrics
    • Respiratory Medicine
    • Epidemiology

    Background:

    • Wheezing is a common symptom in early childhood.
    • Understanding the long-term implications and accurate prevalence of childhood wheeze is crucial for effective management.

    Purpose of the Study:

    • To investigate the prognosis of childhood wheeze based on age of onset.
    • To compare the accuracy of parental recall versus general practice records for identifying early wheezing episodes.

    Main Methods:

    • Retrospective review of general practice records for 369 children at age seven.
    • Comparison of parental questionnaire data with medical records for 174 children.

    Main Results:

    • 31% of children had a record of wheeze, with over half presenting before age three.
    • Earlier onset of wheeze correlated with a better prognosis for wheezing or lower respiratory tract illness at ages five to seven.
    • Parental recall of early wheeze was incomplete and biased by symptom severity and persistence.

    Conclusions:

    • The age of onset is a significant factor in the prognosis of childhood wheeze.
    • Parental questionnaires may underestimate wheeze prevalence in infancy and overestimate persistent wheezing in later childhood due to recall bias.

    More Related Videos

    Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels05:31

    Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

    Published on: August 7, 2017

    Auricular Acupressure as an Adjuvant Treatment for Wheezing in Stable Chronic Obstructive Pulmonary Disease02:34

    Auricular Acupressure as an Adjuvant Treatment for Wheezing in Stable Chronic Obstructive Pulmonary Disease

    Published on: May 10, 2024

    Related Concept Videos

    Asthma: Pathogenesis and Management01:20

    Asthma: Pathogenesis and Management

    Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
    Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
    Asthma-I: Introduction01:29

    Asthma-I: Introduction

    Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
    Asthma-III: Symptoms and Complications01:24

    Asthma-III: Symptoms and Complications

    Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
    Classification of Asthma
    Asthma I: Introduction01:28

    Asthma I: Introduction

    Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
    Asthma III: Clinical Manifestations01:13

    Asthma III: Clinical Manifestations

    Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
    Chronic Obstructive Pulmonary Disease I: Introduction01:23

    Chronic Obstructive Pulmonary Disease I: Introduction

    Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...