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Updated: May 29, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Trends in Blood Pressure Control in US Adult CKD Patients from 1999 to 2018
Anbang Sun1,2, Lin Zhu1, Yanmin Xia3
1Department of Transfusion Medicine, Traditional Chinese and Western Medicine Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Blood pressure control is crucial for chronic kidney disease (CKD) patients. While initially improving, uncontrolled hypertension in CKD patients rose again, highlighting the need for reinforced management, especially for those with high albumin-creatinine rates.
Area of Science:
- Nephrology
- Cardiology
- Public Health
Background:
- Effective blood pressure (BP) control is vital for slowing chronic kidney disease (CKD) progression and preventing cardiovascular complications.
- Hypertension management in CKD patients significantly impacts survival rates.
Purpose of the Study:
- To analyze trends in BP control among adult CKD patients with hypertension in the United States.
- To identify factors associated with uncontrolled BP in this population over time.
Main Methods:
- Utilized National Health and Nutrition Examination Survey (NHANES) data from 1999-2000 to 2017-2018.
- Included 5,510 adult CKD patients with elevated BP or on antihypertensive medication.
Main Results:
- The prevalence of uncontrolled BP in adult CKD patients decreased from 72.9% (1999-2000) to 46.6% (2013-2014) but increased to 56.9% (2017-2018).
- CKD patients with higher albumin-creatinine rates (ACR) were more likely to be on medication but also more likely to have uncontrolled BP.
- Patients with eGFR ≥60 mL/min/1.73m² aware of their hypertension were less likely to take medication compared to those with eGFR 30-59 mL/min/1.73m².
Conclusions:
- BP control efforts in adult CKD patients require reinforcement, particularly for those with ACR ≥300 mg/g.
- Enhancing awareness and adherence to antihypertensive medication is crucial for CKD patients with eGFR ≥60 mL/min/1.73m².
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