Differences of the Chest Images Between Coronavirus Disease 2019 (COVID-19) Patients and Influenza Patients: A

Yingying Han1, Zhijia Wang2, Xingzhao Li3

  • 1Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China, 130000, ORCID: 0000-0002-3583-0448.

Insights

Chest imaging reveals distinct patterns for COVID-19 versus influenza. COVID-19 patients show more peripheral lesions and ground-glass opacities, while pleural effusion is less common.

Area of Science:

  • Radiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Coronavirus disease 2019 (COVID-19) and influenza are significant global health threats.
  • Distinguishing between these viral respiratory illnesses is crucial for effective patient management.

Purpose of the Study:

  • To compare chest imaging findings between COVID-19 and influenza patients.
  • To enhance understanding of the radiological differences between these two diseases.

Main Methods:

  • A systematic literature search was conducted on PubMed, Embase, and Web of Science.
  • A meta-analysis of 26 studies involving 2,159 COVID-19 and 1,568 influenza patients was performed.
  • Chest computed tomography (CT) and X-ray findings were analyzed.

Main Results:

  • COVID-19 patients exhibited more peripheral lung lesions, ground-glass opacities, reverse halo signs, interlobular septal thickening, vascular enlargement, and crazy-paving patterns.
  • Pleural effusion was significantly less common in COVID-19 patients compared to influenza patients.
  • While trends suggested more bilateral and less unilateral lung involvement in COVID-19, these findings lacked statistical significance.

Conclusions:

  • Distinct differences exist in chest imaging manifestations between COVID-19 and influenza.
  • These radiological distinctions can aid in differentiating between the two infectious diseases.

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