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The frequency of lactase phenotypes in Aymara children
Insights
Lactose malabsorption is common in Bolivian Aymara-mixed children, increasing with age. This study found higher rates in older children, indicating a significant age-related trend in lactose intolerance.
Area of Science:
- Pediatrics
- Human Nutrition
- Genetics
Background:
- Lactose malabsorption is a prevalent condition globally, affecting various ethnic groups.
- Understanding the prevalence and age-related trends of lactose malabsorption is crucial for public health initiatives.
Purpose of the Study:
- To determine the prevalence of lactose malabsorption in apparently healthy Bolivian Aymara-mixed children.
- To investigate the relationship between age and the frequency of lactose malabsorption in this population.
Main Methods:
- A total of 122 children aged 2-12 years participated.
- The standard lactose tolerance test with blood glucose determination was employed.
- Participants were analyzed in age groups: 2-5, 6-10, and 11-15 years.
Main Results:
- Lactose malabsorption was observed in 55% of children aged 2-5 years.
- The prevalence increased to 57.4% in the 6-10 years age group.
- A significant rise to 77.4% was noted in children aged 11-15 years.
Conclusions:
- Lactose malabsorption is highly prevalent in Bolivian Aymara-mixed children.
- There is a clear age-related increase in lactose malabsorption frequency within this cohort.
- These findings highlight the need for age-specific nutritional guidance and potential interventions.
Abstract:
A total of 122 apparently healthy Bolivian Aymara-mixed children ranging in age from 2 to 12 years were tested for lactose absorption using the standard lactose tolerance test with blood glucose determination. Analysing the sample according to the age of the probands, we found an increased age related frequency of lactose malabsorption showing final percentages of 55% in the 2 to 5 years group, 57.4% in the 6 to 10 years group, and 77.4% in the 11 to 15 years group.