Related Experiment Video

Updated: May 29, 2025

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
10:27

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on: July 25, 2020

7.2K

Cancer theragnostics: closing the loop for advanced personalized cancer treatment through the platform integration of

Olga V Sergeeva1, Liang Luo2, Anthony Guiseppi-Elie3,4,5

  • 1Genterra JSC, Moscow, Russia.

Frontiers in Bioengineering and Biotechnology
|February 3, 2025
PubMed

Insights

Theranostics offer a promising approach to cancer treatment by integrating diagnostics and therapeutics. This technology enables personalized cancer vaccines and RNA therapy with real-time monitoring for improved patient outcomes.

Area of Science:

  • Oncology
  • Immunology
  • Biotechnology

Background:

  • Conventional cancer treatments like chemotherapy, radiation, and surgery have limitations.
  • RNA therapy and cancer vaccines show promise for personalized cancer treatment with enhanced efficacy and reduced side effects.
  • Predicting patient response and monitoring treatment efficacy in cancer immunotherapy remain significant challenges.

Purpose of the Study:

  • To review the current advancements in theranostics for cancer vaccines and RNA therapy.
  • To explore the application of imaging agents, biomarkers, and diagnostic tools in cancer therapy development and personalization.
  • To discuss the future opportunities and challenges for clinical translation of theranostics in cancer vaccines.

Main Methods:

  • Review of current literature on theranostics for cancer vaccines and RNA therapy.
  • Identification of key diagnostic tools including imaging agents and biomarkers.
  • Analysis of theranostic applications in personalized cancer treatment strategies.

Main Results:

  • Theranostics integrate diagnostic and therapeutic capabilities for real-time monitoring of treatment response.
  • This approach facilitates personalized treatment adjustments in cancer vaccines and RNA therapy.
  • Diagnostic tools are crucial for predicting patient response and optimizing immunotherapy.

Conclusions:

  • Theranostics hold significant potential to overcome challenges in cancer immunotherapy.
  • Real-time monitoring and personalized adjustments are key benefits of theranostic platforms.
  • Further development and clinical translation are essential for realizing the full potential of theranostics in cancer vaccines.
Keywords:
RNA therapybiomarkerscancer vaccinefeedback controlimmunotherapypersonalized medicinetheragnostics

More Related Videos

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies13:24

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Published on: April 11, 2016

11.8K
A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis07:41

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

2.4K

Related Concept Videos

Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.8K
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
47.7K
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
464
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
329
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
321