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Dermatoglyphs in children with mitral valve prolapse
Journal of Medical Genetics
|April 1, 1985
Summary
This study investigated dermatoglyphs in Singaporean children with mitral valve prolapse (MVP), finding no significant difference in digital arch frequency compared to controls. Dermatoglyphic analysis did not reveal other abnormalities in MVP patients.
Area of Science:
- Dermatoglyphics
- Cardiology
- Pediatrics
Background:
- Mitral valve prolapse (MVP) is a cardiac condition affecting heart valve function.
- Dermatoglyphics, the study of fingerprints and palm prints, can offer insights into developmental conditions.
- Previous research suggests potential links between dermatoglyphic patterns and certain congenital abnormalities.
Purpose of the Study:
- To examine the frequency of digital arches in Singaporean school children diagnosed with mitral valve prolapse (MVP).
- To compare dermatoglyphic findings, specifically digital arch patterns, in MVP patients versus a control group.
- To assess for other dermatoglyphic abnormalities in children with MVP.
Main Methods:
- Clinical diagnosis of MVP confirmed by two-dimensional echocardiography in 50 children (35 Chinese, 15 Malay).
- Dermatoglyphic analysis focused on the presence and frequency of digital arches.
- Comparison of arch frequencies with a control group of 50 children without MVP and population data for Singapore.
Main Results:
- Four Chinese children (approximately 11.4%) exhibited digital arches; no Malay children had arches.
- The frequency of digital arches in MVP patients was not statistically higher than in controls.
- No significant differences were observed when compared to general Singaporean Chinese and Malay population arch frequencies (2.0% and 2.9%).
- No other dermatoglyphic abnormalities, including the atd angle, were identified in the MVP group.
Conclusions:
- Digital arch frequency does not appear to be a significant dermatoglyphic marker for mitral valve prolapse in this cohort of Singaporean children.
- Further research may be warranted to explore other potential dermatoglyphic associations with MVP or related conditions.
- Standard dermatoglyphic analysis, including the atd angle, did not reveal additional abnormalities in children with MVP.