Related Experiment Video
Updated: May 29, 2025
Improved Methodology for Studying Postnatal Osteogenesis via Intramembranous Ossification in a Murine Bone Marrow Injury Model
Published on: February 7, 2025
Infantile BCG osteomyelitis ultimately diagnosed as a result of trauma
Katsuhiko Tabata1,2, Osamu Miyazaki1, Ayako Imai1
1Department of Radiology, National Center for Child Health and Development, Setagaya-ku, Tokyo, 157-8535, Japan.
Insights
The Bacillus Calmette-Guérin (BCG) vaccine prevents severe tuberculosis in infants. While rare, BCG osteomyelitis can occur, but typical imaging findings aid definitive diagnosis and rule out other conditions.
Area of Science:
- Pediatrics
- Infectious Diseases
- Radiology
Background:
- The Bacillus Calmette-Guérin (BCG) vaccine is crucial for preventing severe tuberculosis in infants and young children.
- BCG vaccination is standard practice in Japan for infants aged 5-8 months.
- Adverse reactions to BCG are infrequent, but disseminated lymphadenitis and osteomyelitis are known potential complications.
Abstract:
The BCG vaccine is effective in preventing severe tuberculosis infections in infants and young children, and it is commonly administered in Japan to those aged between 5 to 8 months. Although the incidence of adverse reactions is low, disseminated lymphadenitis and osteomyelitis have been reported as potential side effects. We encountered a case of BCG osteomyelitis with typical imaging findings. Provided the clinical presentation and imaging features are recognized, it is possible to diagnose BCG osteomyelitis definitively and exclude a number of possible differential diagnoses.
