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Auditing And Accountability
A Case Study Assessing The Impact Of M&a And Licensing On Fda Drug Approvals Of Leading Pharmaceutical Companies.

Home
Research Domains
Commerce, Management, Tourism And Services
Accounting, Auditing And Accountability
Auditing And Accountability
A Case Study Assessing The Impact Of M&a And Licensing On Fda Drug Approvals Of Leading Pharmaceutical Companies.

Related Experiment Video

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Published on: December 11, 2016

A case study assessing the impact of M&A and licensing on FDA drug approvals of leading pharmaceutical companies.

Alexander Schuhmacher¹, Kyrylo Grinchenko², Oliver Gassmann²

¹Technische Hochschule Ingolstadt Germany; University of St Gallen Switzerland.

Drug Discovery Today

|February 3, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

Leading pharmaceutical companies

Keywords:

FDA approvals M&A Pharma R&D R&D intensity

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Area of Science:

Pharmaceutical R&D and Drug Discovery
Biotechnology and Life Sciences
Healthcare Economics and Management

Background:

Despite increased FDA new drug approvals, pharmaceutical companies face R&D productivity challenges.
Understanding R&D drivers is crucial for optimizing drug development pipelines.
The study addresses the need for better insights into R&D concept context and output correlation.

Purpose of the Study:

To systematically assess the impact of R&D expenditures, R&D intensity, mergers & acquisitions (M&A), and licensing agreements on new drug approvals.
To identify key R&D factors influencing the success of leading pharmaceutical companies.
To provide data-driven insights for strategic R&D investment and decision-making.

Main Methods:

Systematic assessment of R&D data from leading pharmaceutical companies (2012-2021).

R&D productivity

Analysis of correlations between R&D expenditures, R&D intensity, M&A deals, licensing agreements, and new drug approvals.

Statistical evaluation of the impact of various R&D strategies on drug development outcomes.

Main Results:

R&D expenditures show a positive correlation with the number of new drug approvals.
The number of mergers & acquisitions (M&A) deals also correlates positively with new drug approvals.
No significant correlation was found between R&D intensity or licensing agreements and new drug approvals.

Conclusions:

R&D spending and M&A activity are key drivers for new drug approvals in leading pharmaceutical firms.
R&D intensity and licensing agreements appear less impactful on the number of drug approvals.
Strategic focus on R&D investment and M&A may enhance pharmaceutical innovation and market success.