Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

4.0K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.0K
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

68
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
68

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PET molecular imaging of in vivo brain metabolism, synaptic density and glial reactivity changes after neural stem cell transplantation on a rat model of ischemic stroke.

European journal of nuclear medicine and molecular imaging·2026
Same author

Deep integration of clinical metadata with [<sup>18</sup>F]FDG PET/CT imaging for histological subtyping in non-small cell lung cancer: a multi-center study.

European journal of nuclear medicine and molecular imaging·2026
Same author

Baseline amyloid deposition phenotypes inform the spatial distribution of early amyloid clearance with lecanemab in Alzheimer's disease.

European journal of nuclear medicine and molecular imaging·2026
Same author

Bridging the gap to clinical translation: the advanced role of PET molecular imaging in stem cell therapy.

European journal of nuclear medicine and molecular imaging·2026
Same author

Prussian Blue Nanozyme Disrupts the Self-Reinforcing Loop of Tauopathy via Triple-Action Mechanism.

Advanced healthcare materials·2026
Same author

Molecular imaging-guided regenerative medicine: Visualizing <i>in vivo</i> functional behaviors of grafted stem cells.

Innovation (Cambridge (Mass.))·2026

Related Experiment Video

Updated: May 29, 2025

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451
05:17

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451

Published on: April 18, 2025

87

Positron emission tomography molecular imaging for pathological visualization in multiple system atrophy.

La Dong1, Rui Zhou1, Jinyun Zhou1

  • 1Department of Nuclear Medicine and PET Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 31009, China; Institute of Nuclear Medicine and Molecular Imaging of Zhejiang University, Hangzhou, Zhejiang 31009, China; Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, Zhejiang 31009, China.

Neurobiology of Disease
|February 3, 2025
PubMed
Summary

Multiple system atrophy (MSA) is a complex neurodegenerative disease. Positron emission tomography (PET) molecular imaging offers insights into MSA's pathology and potential biomarkers for improved assessment.

Keywords:
Brain metabolismDopaminergic and non-dopaminergic systemInflammationMultiple system atrophyPositron emission tomographyα-Synuclein

More Related Videos

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis
08:40

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

Published on: February 28, 2021

4.0K
Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
05:32

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

6.8K

Related Experiment Videos

Last Updated: May 29, 2025

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451
05:17

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451

Published on: April 18, 2025

87
Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis
08:40

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

Published on: February 28, 2021

4.0K
Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
05:32

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

6.8K

Area of Science:

  • Neuroscience
  • Medical Imaging

Background:

  • Multiple system atrophy (MSA) is a complex neurodegenerative disorder.
  • Its hallmark is abnormal alpha-synuclein aggregation, causing neuroinflammation and system disruption.
  • Brain metabolic abnormalities are also observed in MSA.

Purpose of the Study:

  • To review the pathological mechanisms of MSA.
  • To summarize relevant molecular targets and radiopharmaceuticals for PET imaging.
  • To discuss clinical applications and future directions of PET in MSA.

Main Methods:

  • Review of existing literature on MSA pathology and PET imaging.
  • Identification of key pathological processes and molecular targets.
  • Analysis of radiopharmaceuticals and their application in PET studies.

Main Results:

  • PET imaging visualizes, characterizes, and quantifies MSA pathological processes.
  • Radiolabeled agents enable diverse perspectives on molecular events.
  • PET provides insights into MSA pathomechanisms.

Conclusions:

  • PET molecular imaging is a promising tool for understanding MSA.
  • Development of PET imaging biomarkers can enhance disease assessment and management.
  • Further research into PET applications holds significant future potential for MSA.