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Updated: Jun 14, 2025
05:46
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
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Secondary open-angle glaucoma as an initial presentation of diffuse iris melanoma.
Emiel Matthys1, Guy Missotten1, Rita Van Ginderdeuren1
1Ophthalmology, UZ Leuven, Leuven, Flanders, Belgium.
BMJ Case Reports
|February 3, 2025
Summary
A rare case of secondary open-angle glaucoma caused by iris melanoma highlights the need to consider secondary causes for unilateral glaucoma. Gonioscopy is crucial for diagnosing this rare but significant condition.
Area of Science:
- Ophthalmology
- Oncology
Background:
- Secondary open-angle glaucoma can present unilaterally.
- Iris melanoma is a rare cause of secondary glaucoma.
Purpose of the Study:
- To report a case of secondary open-angle glaucoma due to iris melanoma.
- To emphasize the importance of gonioscopy in diagnosing unilateral glaucoma.
Main Methods:
- Case report of a patient with unilateral, uncontrolled intraocular pressure.
- Slit-lamp examination and gonioscopy revealing iris pigmentation and an inferior angle mass.
- Biopsy confirming pigmented iris melanoma.
- Systemic work-up to rule out metastasis.
Main Results:
- Diagnosis of secondary open-angle glaucoma secondary to diffuse iris melanoma.
- Patient underwent enucleation for treatment.
- Systemic work-up negative for metastatic disease.
Conclusions:
- Unilateral or asymmetric glaucoma warrants investigation for secondary causes like iris melanoma.
- Gonioscopy is a vital diagnostic tool in such cases.
- Early diagnosis and management of secondary glaucoma due to intraocular tumors are critical.
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