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Related Concept Videos

Motor Unit Stimulation01:20

Motor Unit Stimulation

When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...

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Related Experiment Video

Updated: Jun 23, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
04:29

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

Right-sided vagus nerve stimulation: Worldwide collection and perspectives.

Marc Zanello1,2,3, Berthold Voges4, Ramesh Chelvarajah5,6

  • 1Department of Neurosurgery, GHU Paris - Sainte-Anne Hospital, Paris, France.

Annals of Clinical and Translational Neurology
|February 4, 2025
PubMed
Summary
This summary is machine-generated.

Right-sided vagus nerve stimulation (VNS) for drug-resistant epilepsy is effective, with over half of patients responding. While comparable to left-sided VNS, right-sided VNS may have lower tolerability.

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Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS): Technique, Targeting, and Considerations
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Implantation Surgery for Abdominal Vagus Nerve Stimulation and Recording Studies in Awake Rats

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Last Updated: Jun 23, 2026

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Implantation Surgery for Abdominal Vagus Nerve Stimulation and Recording Studies in Awake Rats
07:17

Implantation Surgery for Abdominal Vagus Nerve Stimulation and Recording Studies in Awake Rats

Published on: January 19, 2024

Area of Science:

  • Neurology
  • Neurosurgery
  • Epilepsy Treatment

Background:

  • Vagus nerve stimulation (VNS) is a standard therapy for drug-resistant epilepsy (DRE).
  • Implantation is typically on the left vagus nerve.
  • Data on right-sided VNS is scarce, with only seven published cases.

Purpose of the Study:

  • To investigate the safety and effectiveness of right-sided VNS in DRE.
  • To augment the limited literature on this alternative VNS approach.

Main Methods:

  • An anonymous 38-item questionnaire was distributed to expert surgeons.
  • The survey collected data on patient demographics, reasons for right-sided implantation, and outcomes.
  • Thirty-eight cases of right-sided VNS were analyzed.

Main Results:

  • Right-sided VNS was performed due to lead issues, anatomical constraints, infection, or shunts.
  • 55% of patients were responders, with a mean seizure frequency reduction of 56.2%.
  • Effectiveness was comparable to left-sided VNS, though tolerability might be lower, with three patients discontinuing treatment.

Conclusions:

  • This multicenter case series expands the understanding of right-sided VNS.
  • Right-sided VNS demonstrates comparable effectiveness to left-sided VNS.
  • Further research is needed to fully assess the safety and efficacy of right-sided VNS.