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Updated: May 29, 2025

Facile Preparation and Photoactivation of Prodrug-Dye Nanoassemblies
Published on: February 17, 2023
Hypoxia-responsive bilirubin supramolecular nanoprodrugs for targeted photothermal-chemotherapy
Yu Xie1, Liangshun Zheng1, Tingting Chen1
1School of Chemistry and Chemical Engineering, Nantong University, Nantong, 226019, P. R. China. yueding@ntu.edu.cn.
Abstract:
A bilirubin supramolecular nanoprodrug (SCBR/TPZ) with enhanced cellular uptake towards the HepG2 cell line was constructed based on host-guest recognition, which provided an innovative strategy to design a hypoxia-responsive BR supramolecular nanoprodrug for lactose-targeted photothermal-chemotherapy (PTT-CT) with a synergistic effect towards HepG2.
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