An Imidazo-Pyridin-Derived Fluorescent Probe for Monitoring Hydrogen Sulfide in Chinese Medicinal Materials

Herein, an imidazo-pyridin-derived fluorescent probe ImPy-HS was developed for monitoring the hydrogen sulfide (H₂S) level in the water decoction of Chinese medicinal materials. Under the excitation at 355 nm, ImPy-HS exhibited the obvious fluorescence response at 490 nm. The detection system with ImPy-HS showed the advantages including relatively high sensitivity, high selectivity, and high steadiness. Especially, in the water decoction of Chinese medicinal materials with H₂S from both addition and excessive fumigation then reduction, ImPy-HS achieved the monitoring of the H₂S level. ImPy-HS also realized the imaging of both exogenous and endogenous H₂S as well as the water decoction-treated affection. The information here was meaningful for studying the quality control of Chinese medicinal materials.