Related Experiment Video
Updated: May 29, 2025

A Murine Model of Vertical Sleeve Gastrectomy
Published on: December 18, 2017
Short-Term Outcomes of Laparoscopic Sleeve Gastrectomy for Weight Loss and Gastroesophageal Reflux Disease
Mian S Yousaf1, Noman Khan2, Ghulam Fareed3
1Gastroenterology, Prime Teaching Hospital, Peshawar, PAK.
Abstract:
Background and objective Laparoscopic sleeve gastrectomy (LSG), a novel bariatric technique, reduces stomach capacity to promote weight loss. It is increasingly preferred due to its lower risk and improved outcomes, particularly for obesity-associated hypertension and diabetes. LSG has also demonstrated effective weight loss. This study aimed to evaluate the short-term outcomes of LSG for treating obesity and gastroesophageal reflux disease (GERD). Methodology A prospective cohort study was conducted at Lady Reading Hospital-Medical Teaching Institute (LRH-MTI), Peshawar, from March 2023 to February 2024. A total of 280 patients (aged 18-60 years) were selected using a consecutive sampling technique. Weight loss was assessed using the percentage of total body weight loss (%TBWL) and excess weight loss (%EWL). GERD symptoms were evaluated using the GerdQ score. Statistical analyses, including paired t-tests and Chi-squared tests, were performed using SPSS version 26 (IBM Inc., Armonk, New York), with significance set at p<0.05. Results LSG achieved a 100% success rate with no major complications, an average surgery duration of 45 minutes, and a mean hospital stay of 2.5 days. At the 12-month follow-up, significant reductions in hypertension (p=0.032) and diabetes (p<0.012) were observed. Substantial weight loss (p=0.001) and a decrease in comorbidities were noted, while GERD symptom improvement was not statistically significant (p=0.348). Conclusion LSG is a promising intervention for weight loss and obesity-related comorbidities. It significantly improves hypertension and diabetes, although its impact on GERD requires further research. Longer follow-ups and diverse populations are recommended for future studies.
Related Concept Videos
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:

